Fatigue

Adrenal Fatigue
Adrenal fatigue, known as tired adrenal glands, happens when the adrenal glands cut down hormone production after long-term severe stress or trauma. This mainly affects cortisol and DHEA levels. Initially, the adrenal glands boost cortisol and DHEA production in response to stress. Research shows that prolonged stress leads to a decrease in DHEA. Thus, measuring both cortisol and DHEA is vital to evaluate adrenal function and provide the right support.
DHEA
Low DHEA levels can cause symptoms like fatigue, depression, low libido, and obesity. High levels, on the other hand, might lead to PCOS, acne, and hair loss. People with chronic fatigue syndrome (CFS) commonly have low DHEA levels.
Cortisol
Since cortisol levels fluctuate during the day, it's important to measure them multiple times to get a full picture of adrenal cortisol production. Ideally, cortisol levels should be highest in the morning and decrease as the day progresses. Today, many people show abnormal cortisol patterns, including levels that are too low, high, flat, or even inverted. This test specifically measures bioavailable free cortisol seven times in a single day, as only free cortisol is biologically active.
How Does the Adrenal Test Work?
You receive two saliva test kits to use at home. The cortisol samples are taken seven times in one day, and the DHEA samples twice in the morning. Once you collect the samples, send them to our lab. Your digital test results will be available as soon as our lab finishes analyzing your samples.

GetTested's Vitamin B12 test
GetTested's Vitamin B12 test is designed to accurately trace for B12 in the blood. 
Whereas traditional tests measure the total B12 in the body, encompassing both inactive and active forms, GetTested's Vitamin B12 test specifically measures holotranscobalamin, which is the active form of B12. This marker is more sensitive than MMA (methyl malonate), making it a reliable indicator of B12 deficiency. 
Measure your B12 levels with our vitamin b12 test kit, delivered to your door and convenient to use at home. If you suspect you may have a Vitamin B12 deficiency, test for B12 now and quickly gain insights into your health. 
About Vitamin B12
Vitamin B12, a crucial water-soluble vitamin, plays a vital role in our bodies. Unlike other vitamins, our body cannot produce B12, making dietary intake essential. There are two forms of Vitamin B12: an active form known as Active B12, bound to the protein transcobalamin, and an inactive form. Cells in the body utilise the active form.
One key function of B12 involves DNA production. Without B12, cells cannot divide properly, hindering the replacement of damaged or malfunctioning cells. B12 also contributes to nerve myelination (creating insulating fats around nerves) and breaks down homocysteine, a by-product of protein metabolism.
B12's Unique Absorption Process
Despite being water-soluble, B12 does not dissolve well in water or fat. Its absorption requires a special mechanism involving the intrinsic factor (IF), produced by stomach wall cells. This factor binds to B12, facilitating its transport through the intestinal wall, into the blood, and eventually to the liver. Here, it is stored or distributed throughout the body.
The liver can store B12 for up to 20 years. Unlike other B vitamins, regular B12 intake isn't necessary if liver reserves are sufficient. However, certain groups, including vegans, alcoholics, and individuals who have had bariatric surgery, face a higher risk of B12 deficiency. This risk arises from a potential reduction in intrinsic factor production, crucial for B12 absorption.
Symptoms of a B12 deficiency
A Vitamin B12 deficiency can cause a variety of symptoms that usually develop gradually. If untreated, these conditions can get worse.  
Most common symptoms of vitamin B12 include: 

Fatigue and weakness
Shortness of breath 
Stomach pain
Diarrhoea 

Vitamin B12 deficiency can also have an affect on mental well-being and cause:

Headaches,
Feelings of depression 
Anxiety 
Problems with memory

Symptoms of this deficiency range from mild (like fatigue and weakness) to more severe issues like heart palpitations, aforementioned mental health problems, and neurological symptoms. These symptoms may progress to pernicious anaemia or nerve-related issues like tingling, muscle weakness, and "burning feet syndrome," a result of inadequate myelin formation around nerves. 
Vegans and B12 Deficiency
Vitamin B12 naturally occurs in animal-based foods, placing vegans at a heightened risk of deficiency. For vegans, supplementing B12 is vital. The extent of deficiency largely depends on the liver's stored B12 levels at the time of switching to a vegan diet.

Who is the DNA Fatigue Test Suitable For?
The DNA Fatigue Test is designed for anyone seeking to understand the roots of their fatigue and low energy levels. It's especially valuable for individuals experiencing chronic fatigue, anemia, sleep disturbances, mood swings, and other energy-related issues.
How Does It Work?

Order the Test: Order your GetTested DNA Fatigue Test online and have it delivered to your home.
Collect the Sample: Use the provided test kit to easily collect a saliva sample at home.
Return the Sample: Place the sample in the prepaid return envelope and send it back to the GetTested laboratory.
The Results: Within 6-8 weeks of receiving your sample, we analyze your genes and generate a comprehensive response report.

Test Report and Recommendations
Once your results are ready, you will receive a comprehensive response report from GetTested explaining your genetic insights and what they mean for your health. In addition, the report includes personalized recommendations and strategies to optimize your health based on your genetic results.
About the Sample Material
The DNA and original sample material are destroyed after analysis, and there is no personal connection to the sample except for your unique test ID to which your test results are linked. The information is completely anonymized, and the lab has no knowledge of whom it belongs to. We do not give or sell the results to any third party. You also have the option to remove your test results after receiving them.